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Pharmacokinetic / pharmacodynamic relationships of liposomal amphotericin B and miltefosine in experimental visceral leishmaniasis

BACKGROUND: There is a continued need to develop effective and safe treatments for visceral leishmaniasis (VL). Preclinical studies on pharmacokinetics and pharmacodynamics of anti-infective agents, such as anti-bacterials and anti-fungals, have provided valuable information in the development and d...

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Detalles Bibliográficos
Autores principales: Voak, Andrew A., Harris, Andy, Coteron-Lopez, Jose Miguel, Angulo-Barturen, Iñigo, Ferrer-Bazaga, Santiago, Croft, Simon L., Seifert, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924795/
https://www.ncbi.nlm.nih.gov/pubmed/33651812
http://dx.doi.org/10.1371/journal.pntd.0009013