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Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni

Schistosomiasis is a neglected tropical disease that currently affects over 250 million individuals worldwide. In the absence of an immunoprophylactic vaccine and the recognition that mono-chemotherapeutic control of schistosomiasis by praziquantel has limitations, new strategies for managing diseas...

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Detalles Bibliográficos
Autores principales: Craven, Holly M., Bonsignore, Riccardo, Lenis, Vasilis, Santi, Nicolo, Berrar, Daniel, Swain, Martin, Whiteland, Helen, Casini, Angela, Hoffmann, Karl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924807/
https://www.ncbi.nlm.nih.gov/pubmed/33600427
http://dx.doi.org/10.1371/journal.pntd.0008770