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Influence of dapivirine vaginal ring use on cervicovaginal immunity and functional microbiome in adolescent girls

OBJECTIVE: The antiretroviral-based dapivirine vaginal ring reduced HIV risk among women in phase III clinical trials. However, limited data exists on the impact of dapivirine on the vaginal microenvironment in adolescents. DESIGN: A comprehensive metaproteomics approach was used to assess host prot...

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Detalles Bibliográficos
Autores principales: Farr Zuend, Christina, Noël-Romas, Laura, Hoger, Sarah, McCorriser, Stuart, Westmacott, Garrett, Marrazzo, Jeanne, Hillier, Sharon L., Dezzutti, Charlene, Squires, Kathleen, Bunge, Katherine E., Burgener, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924934/
https://www.ncbi.nlm.nih.gov/pubmed/33181534
http://dx.doi.org/10.1097/QAD.0000000000002751