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tRNA sequences can assemble into a replicator

Can replication and translation emerge in a single mechanism via self-assembly? The key molecule, transfer RNA (tRNA), is one of the most ancient molecules and contains the genetic code. Our experiments show how a pool of oligonucleotides, adapted with minor mutations from tRNA, spontaneously formed...

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Detalles Bibliográficos
Autores principales: Kühnlein, Alexandra, Lanzmich, Simon A, Braun, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924937/
https://www.ncbi.nlm.nih.gov/pubmed/33648631
http://dx.doi.org/10.7554/eLife.63431