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Mitochondrial copper and phosphate transporter specificity was defined early in the evolution of eukaryotes

The mitochondrial carrier family protein SLC25A3 transports both copper and phosphate in mammals, yet in Saccharomyces cerevisiae the transport of these substrates is partitioned across two paralogs: PIC2 and MIR1. To understand the ancestral state of copper and phosphate transport in mitochondria,...

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Detalles Bibliográficos
Autores principales: Zhu, Xinyu, Boulet, Aren, Buckley, Katherine M, Phillips, Casey B, Gammon, Micah G, Oldfather, Laura E, Moore, Stanley A, Leary, Scot C, Cobine, Paul A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924939/
https://www.ncbi.nlm.nih.gov/pubmed/33591272
http://dx.doi.org/10.7554/eLife.64690