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Optogenetic control of PRC1 reveals its role in chromosome alignment on the spindle by overlap length-dependent forces
During metaphase, chromosome position at the spindle equator is regulated by the forces exerted by kinetochore microtubules and polar ejection forces. However, the role of forces arising from mechanical coupling of sister kinetochore fibers with bridging fibers in chromosome alignment is unknown. He...
Autores principales: | Jagrić, Mihaela, Risteski, Patrik, Martinčić, Jelena, Milas, Ana, Tolić, Iva M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924949/ https://www.ncbi.nlm.nih.gov/pubmed/33480356 http://dx.doi.org/10.7554/eLife.61170 |
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