Single molecule microscopy reveals key physical features of repair foci in living cells

In response to double strand breaks (DSB), repair proteins accumulate at damaged sites, forming membrane-less sub-compartments or foci. Here we explored the physical nature of these foci, using single molecule microscopy in living cells. Rad52, the functional homolog of BRCA2 in yeast, accumulates a...

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Detalles Bibliográficos
Autores principales: Miné-Hattab, Judith, Heltberg, Mathias, Villemeur, Marie, Guedj, Chloé, Mora, Thierry, Walczak, Aleksandra M, Dahan, Maxime, Taddei, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Physics of Living Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924958/
https://www.ncbi.nlm.nih.gov/pubmed/33543712
http://dx.doi.org/10.7554/eLife.60577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924958/
https://www.ncbi.nlm.nih.gov/pubmed/33543712
http://dx.doi.org/10.7554/eLife.60577

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