UPLC-MS/MS for the Herb-Drug Interactions of Xiao-Ai-Ping Injection on Enasidenib in Rats Based on Pharmacokinetics

OBJECTIVE: To develop and validate a sensitive and rapid ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the determination of enasidenib in rat plasma and to investigate the effect of Xiao-ai-ping injection (XAPI) on the pharmacokinetics of enasidenib in rats....

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Bo-wen, Qiu, Cheng-zheng, Tang, Chang-qian, Zhang, Jia-hui, Zhang, Yi, Du, Qi-guang, Feng, Yi, Qiu, Xiang-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925021/
https://www.ncbi.nlm.nih.gov/pubmed/33688498
http://dx.doi.org/10.1155/2021/6636266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925021/
https://www.ncbi.nlm.nih.gov/pubmed/33688498
http://dx.doi.org/10.1155/2021/6636266

Ejemplares similares