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UPLC-MS/MS for the Herb-Drug Interactions of Xiao-Ai-Ping Injection on Enasidenib in Rats Based on Pharmacokinetics

OBJECTIVE: To develop and validate a sensitive and rapid ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the determination of enasidenib in rat plasma and to investigate the effect of Xiao-ai-ping injection (XAPI) on the pharmacokinetics of enasidenib in rats....

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Detalles Bibliográficos
Autores principales:	Wang, Bo-wen, Qiu, Cheng-zheng, Tang, Chang-qian, Zhang, Jia-hui, Zhang, Yi, Du, Qi-guang, Feng, Yi, Qiu, Xiang-jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925021/ https://www.ncbi.nlm.nih.gov/pubmed/33688498 http://dx.doi.org/10.1155/2021/6636266

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