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Celecoxib-Loaded Electrospun Fibrous Antiadhesion Membranes Reduce COX-2/PGE(2) Induced Inflammation and Epidural Fibrosis in a Rat Failed Back Surgery Syndrome Model

To date, failed back surgery syndrome (FBSS) remains a therapy-refractory clinical condition after spinal surgery. The antiadhesion membrane is applied to prevent FBSS by isolating fibrosis; however, the inflammation stimulated by the foreign body and surgical trauma needs to be further resolved sim...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Wang, Yunhao, Lou, Tengfei, Ding, Mingqian, Li, Juehong, Xiong, Hao, Yao, Zhixiao, Ma, Yingying, Chen, Huajiang, Liu, Shenghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925049/
https://www.ncbi.nlm.nih.gov/pubmed/33679970
http://dx.doi.org/10.1155/2021/6684176