Cargando…

Acupuncture for Chronic Pain-Related Depression: A Systematic Review and Meta-Analysis

OBJECTIVE: The aim of this systematic review was to summarize and evaluate the existing evidence on the effectiveness and safety of acupuncture in relieving chronic pain-related depression (CPRD). METHODS: We searched seven online databases to identify eligible randomized controlled trials (RCTs) of...

Descripción completa

Detalles Bibliográficos
Autores principales: You, Jianyu, Li, Haiyan, Xie, Dingyi, Chen, Rixin, Chen, Mingren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925064/
https://www.ncbi.nlm.nih.gov/pubmed/33680223
http://dx.doi.org/10.1155/2021/6617075
_version_ 1783659215553822720
author You, Jianyu
Li, Haiyan
Xie, Dingyi
Chen, Rixin
Chen, Mingren
author_facet You, Jianyu
Li, Haiyan
Xie, Dingyi
Chen, Rixin
Chen, Mingren
author_sort You, Jianyu
collection PubMed
description OBJECTIVE: The aim of this systematic review was to summarize and evaluate the existing evidence on the effectiveness and safety of acupuncture in relieving chronic pain-related depression (CPRD). METHODS: We searched seven online databases to identify eligible randomized controlled trials (RCTs) of acupuncture for CPRD published before September 2020. We included studies that used acupuncture as the intervention group, with or without a control group, and the control group was treated with conventional drugs. Meta-analysis was performed using RevMan 5.3 software. For outcomes, assessments were performed using the Hamilton Depression Scale (HAMD), Visual Analogue Scale (VAS), and adverse events. RESULTS: Eight studies involving 636 participants were identified and included in the meta-analysis. The results showed that single acupuncture treatment and drug treatment have the same effect in improving the HAMD score (MD = −0.14, 95% CI = [−0.88, 0.59], P = 0.71) and alleviating the VAS score (MD = −0.42, 95% CI = [−1.10, −0.27], P = 0.23), but acupuncture treatment is safer (OR = 0.03, 95% CI = [0.01, 0.21], P = 0.0003). In addition, acupuncture combined with drugs (control group) is more beneficial than single-drug treatment in improving the HAMD score (MD = −2.95, 95% CI = [−3.55, −2.36], P < 0.00001) and alleviating the VAS score (MD = −1.06, 95% CI = [−1.65, −0.47], P = 0.0004). CONCLUSION: Acupuncture is an effective and safe treatment for CPRD, and acupuncture combined with drug therapy is more effective than single-drug therapy. Nevertheless, the conclusions were limited due to the low quality and a small number of included studies.
format Online
Article
Text
id pubmed-7925064
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-79250642021-03-04 Acupuncture for Chronic Pain-Related Depression: A Systematic Review and Meta-Analysis You, Jianyu Li, Haiyan Xie, Dingyi Chen, Rixin Chen, Mingren Pain Res Manag Review Article OBJECTIVE: The aim of this systematic review was to summarize and evaluate the existing evidence on the effectiveness and safety of acupuncture in relieving chronic pain-related depression (CPRD). METHODS: We searched seven online databases to identify eligible randomized controlled trials (RCTs) of acupuncture for CPRD published before September 2020. We included studies that used acupuncture as the intervention group, with or without a control group, and the control group was treated with conventional drugs. Meta-analysis was performed using RevMan 5.3 software. For outcomes, assessments were performed using the Hamilton Depression Scale (HAMD), Visual Analogue Scale (VAS), and adverse events. RESULTS: Eight studies involving 636 participants were identified and included in the meta-analysis. The results showed that single acupuncture treatment and drug treatment have the same effect in improving the HAMD score (MD = −0.14, 95% CI = [−0.88, 0.59], P = 0.71) and alleviating the VAS score (MD = −0.42, 95% CI = [−1.10, −0.27], P = 0.23), but acupuncture treatment is safer (OR = 0.03, 95% CI = [0.01, 0.21], P = 0.0003). In addition, acupuncture combined with drugs (control group) is more beneficial than single-drug treatment in improving the HAMD score (MD = −2.95, 95% CI = [−3.55, −2.36], P < 0.00001) and alleviating the VAS score (MD = −1.06, 95% CI = [−1.65, −0.47], P = 0.0004). CONCLUSION: Acupuncture is an effective and safe treatment for CPRD, and acupuncture combined with drug therapy is more effective than single-drug therapy. Nevertheless, the conclusions were limited due to the low quality and a small number of included studies. Hindawi 2021-02-22 /pmc/articles/PMC7925064/ /pubmed/33680223 http://dx.doi.org/10.1155/2021/6617075 Text en Copyright © 2021 Jianyu You et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
You, Jianyu
Li, Haiyan
Xie, Dingyi
Chen, Rixin
Chen, Mingren
Acupuncture for Chronic Pain-Related Depression: A Systematic Review and Meta-Analysis
title Acupuncture for Chronic Pain-Related Depression: A Systematic Review and Meta-Analysis
title_full Acupuncture for Chronic Pain-Related Depression: A Systematic Review and Meta-Analysis
title_fullStr Acupuncture for Chronic Pain-Related Depression: A Systematic Review and Meta-Analysis
title_full_unstemmed Acupuncture for Chronic Pain-Related Depression: A Systematic Review and Meta-Analysis
title_short Acupuncture for Chronic Pain-Related Depression: A Systematic Review and Meta-Analysis
title_sort acupuncture for chronic pain-related depression: a systematic review and meta-analysis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925064/
https://www.ncbi.nlm.nih.gov/pubmed/33680223
http://dx.doi.org/10.1155/2021/6617075
work_keys_str_mv AT youjianyu acupunctureforchronicpainrelateddepressionasystematicreviewandmetaanalysis
AT lihaiyan acupunctureforchronicpainrelateddepressionasystematicreviewandmetaanalysis
AT xiedingyi acupunctureforchronicpainrelateddepressionasystematicreviewandmetaanalysis
AT chenrixin acupunctureforchronicpainrelateddepressionasystematicreviewandmetaanalysis
AT chenmingren acupunctureforchronicpainrelateddepressionasystematicreviewandmetaanalysis