Deep Gene Sequence Cluster Analyses of Multi-Virus-Infected Mucosal Tissue Reveal Enhanced Transmission of Acute HIV-1

Exposure of the genital mucosa to a genetically diverse viral swarm from the donor HIV-1 can result in breakthrough and systemic infection by a single transmitted/founder (TF) virus in the recipient. The highly diverse HIV-1 envelope (Env) in this inoculating viral swarm may have a critical role in...

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Detalles Bibliográficos
Autores principales: Klein, Katja, Nankya, Immaculate, Nickel, Gabrielle, Ratcliff, Annette N., Meadows, Adam A. J., Hathaway, Nicholas, Bailey, Jeffrey A., Stieh, Daniel J., Cheeseman, Hannah M., Carias, Ann M., Lobritz, Michael A., Mann, Jamie F. S., Gao, Yong, Hope, Thomas J., Shattock, Robin J., Arts, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925087/
https://www.ncbi.nlm.nih.gov/pubmed/33177204
http://dx.doi.org/10.1128/JVI.01737-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925087/
https://www.ncbi.nlm.nih.gov/pubmed/33177204
http://dx.doi.org/10.1128/JVI.01737-20

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