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Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers

The induction of broadly neutralizing antibodies (bNAbs) is a major goal in vaccine research. HIV-1-infected individuals that develop exceptionally strong bNAb responses, termed elite neutralizers, can inform vaccine design by providing blueprints for the induction of similar bNAb responses. We desc...

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Detalles Bibliográficos
Autores principales: Schorcht, Anna, van den Kerkhof, Tom L. G. M., Cottrell, Christopher A., Allen, Joel D., Torres, Jonathan L., Behrens, Anna-Janina, Schermer, Edith E., Burger, Judith A., de Taeye, Steven W., Torrents de la Peña, Alba, Bontjer, Ilja, Gumbs, Stephanie, Ozorowski, Gabriel, LaBranche, Celia C., de Val, Natalia, Yasmeen, Anila, Klasse, Per Johan, Montefiori, David C., Moore, John P., Schuitemaker, Hanneke, Crispin, Max, van Gils, Marit J., Ward, Andrew B., Sanders, Rogier W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925178/
https://www.ncbi.nlm.nih.gov/pubmed/32999024
http://dx.doi.org/10.1128/JVI.01214-20