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Quaternary stereocentres via catalytic enantioconvergent nucleophilic substitution reactions of tertiary alkyl halides by alkenylmetal reagents

The development of efficient methods, particularly catalytic and enantioselective processes, for the construction of all-carbon quaternary stereocentres is an important (and difficult) challenge in organic synthesis, due to the occurrence of this motif in a range of bioactive molecules. One conceptu...

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Detalles Bibliográficos
Autores principales: Wang, Zhaobin, Yang, Ze-Peng, Fu, Gregory C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925339/
https://www.ncbi.nlm.nih.gov/pubmed/33432109
http://dx.doi.org/10.1038/s41557-020-00609-7