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Single nucleotide polymorphisms in interleukin-6 attenuates hepatocytes injury in hypoxia/re-oxygenation via STAT3 signal pathway mediated autophagy

Ischemia-reperfusion injury (IRI) is inevitable during liver surgery, and it is an important factor affecting the prognosis of patients. IL-6 rs1800796 single nucleotide polymorphisms (SNPs) can promote synthesis and secretion of IL-6 and protect hepatocytes from IRI. In this study, we investigated...

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Detalles Bibliográficos
Autores principales: Tang, Hongwei, Fang, Hongbo, Guo, Wenzhi, Cao, Shengli, Guo, Danfeng, Zhang, Huapeng, Gao, Jie, Zhang, Shuijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925450/
https://www.ncbi.nlm.nih.gov/pubmed/33484391
http://dx.doi.org/10.1007/s11033-020-06090-2