Cargando…

A synthetic peptide as an allosteric inhibitor of human arginase I and II

Arginine metabolism mediated by arginases plays a critical role in cell and tissue function. The arginine hydrolysis is deeply involved in the urea cycle, which helps the kidney excrete ammonia from blood. Upregulation of arginases affects microenvironment stability due to the presence of excess ure...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Kai, Lunev, Sergey, van den Berg, Mariska P. M., Al-Dahmani, Zayana M., Evans, Stephen, Mertens, Dyon A. L. J., Meurs, Herman, Gosens, Reinoud, Groves, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925462/
https://www.ncbi.nlm.nih.gov/pubmed/33590412
http://dx.doi.org/10.1007/s11033-021-06176-5