Cargando…
A synthetic peptide as an allosteric inhibitor of human arginase I and II
Arginine metabolism mediated by arginases plays a critical role in cell and tissue function. The arginine hydrolysis is deeply involved in the urea cycle, which helps the kidney excrete ammonia from blood. Upregulation of arginases affects microenvironment stability due to the presence of excess ure...
Autores principales: | Gao, Kai, Lunev, Sergey, van den Berg, Mariska P. M., Al-Dahmani, Zayana M., Evans, Stephen, Mertens, Dyon A. L. J., Meurs, Herman, Gosens, Reinoud, Groves, Matthew R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925462/ https://www.ncbi.nlm.nih.gov/pubmed/33590412 http://dx.doi.org/10.1007/s11033-021-06176-5 |
Ejemplares similares
-
Arginase and pulmonary diseases
por: Maarsingh, Harm, et al.
Publicado: (2008) -
The GSK-3/β-catenin-signalling axis in smooth muscle and its relationship with remodelling
por: Gosens, Reinoud, et al.
Publicado: (2008) -
Airway and Extracellular Matrix Mechanics in COPD
por: Bidan, Cécile M., et al.
Publicado: (2015) -
Muscarinic receptor signaling in the pathophysiology of asthma and COPD
por: Gosens, Reinoud, et al.
Publicado: (2006) -
Thiosulfate sulfurtransferase prevents hyperglycemic damage to the zebrafish pronephros in an experimental model for diabetes
por: Al-Dahmani, Zayana M., et al.
Publicado: (2022)