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Thymic origins of autoimmunity—lessons from inborn errors of immunity
During their intrathymic development, nascent T cells are empowered to protect against pathogens and to be operative for a life-long acceptance of self. While autoreactive effector T (Teff) cell progenitors are eliminated by clonal deletion, the intrathymic mechanisms by which thymic regulatory T ce...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925499/ https://www.ncbi.nlm.nih.gov/pubmed/33532929 http://dx.doi.org/10.1007/s00281-020-00835-8 |