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Targeted biologic inhibition of both tumor cell-intrinsic and intercellular CLPTM1L/CRR9-mediated chemotherapeutic drug resistance

Recurrence of therapy-resistant tumors is a principal problem in solid tumor oncology, particularly in ovarian cancer. Despite common complete responses to first line, platinum-based therapies, most women with ovarian cancer recur, and eventually, nearly all with recurrent disease develop platinum r...

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Detalles Bibliográficos
Autores principales: Parashar, Deepak, Geethadevi, Anjali, McAllister, Donna, Ebben, Johnathan, Peterson, Francis C., Jensen, Davin R., Bishop, Erin, Pradeep, Sunila, Volkman, Brian F., Dwinell, Michael B., Chaluvally-Raghavan, Pradeep, James, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925570/
https://www.ncbi.nlm.nih.gov/pubmed/33654182
http://dx.doi.org/10.1038/s41698-021-00152-9