Identification of genetic factors influencing metabolic dysregulation and retinal support for MacTel, a retinal disorder

Macular Telangiectasia Type 2 (MacTel) is a rare degenerative retinal disease with complex genetic architecture. We performed a genome-wide association study on 1,067 MacTel patients and 3,799 controls, which identified eight novel genome-wide significant loci (p < 5 × 10(−8)), and confirmed all...

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Detalles Bibliográficos
Autores principales: Bonelli, Roberto, Jackson, Victoria E., Prasad, Aravind, Munro, Jacob E., Farashi, Samaneh, Heeren, Tjebo F. C., Pontikos, Nikolas, Scheppke, Lea, Friedlander, Martin, Egan, Catherine A., Allikmets, Rando, Ansell, Brendan R. E., Bahlo, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925591/
https://www.ncbi.nlm.nih.gov/pubmed/33654266
http://dx.doi.org/10.1038/s42003-021-01788-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925591/
https://www.ncbi.nlm.nih.gov/pubmed/33654266
http://dx.doi.org/10.1038/s42003-021-01788-w

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