Structural variant detection in cancer genomes: computational challenges and perspectives for precision oncology

Cancer is generally characterized by acquired genomic aberrations in a broad spectrum of types and sizes, ranging from single nucleotide variants to structural variants (SVs). At least 30% of cancers have a known pathogenic SV used in diagnosis or treatment stratification. However, research into the...

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Detalles Bibliográficos
Autores principales: van Belzen, Ianthe A. E. M., Schönhuth, Alexander, Kemmeren, Patrick, Hehir-Kwa, Jayne Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925608/
https://www.ncbi.nlm.nih.gov/pubmed/33654267
http://dx.doi.org/10.1038/s41698-021-00155-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925608/
https://www.ncbi.nlm.nih.gov/pubmed/33654267
http://dx.doi.org/10.1038/s41698-021-00155-6

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