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Administration of GDF3 Into Septic Mice Improves Survival via Enhancing LXRα-Mediated Macrophage Phagocytosis

The defective eradication of invading pathogens is a major cause of death in sepsis. As professional phagocytic cells, macrophages actively engulf/kill microorganisms and play essential roles in innate immune response against pathogens. Growth differentiation factor 3 (GDF3) was previously implicate...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Mu, Xingjiang, Zhao, Hongyan, Li, Yutian, Wang, Lu, Wolfe, Vivian, Cui, Shu-Nan, Wang, Xiaohong, Peng, Tianqing, Zingarelli, Basilia, Wang, Chunting, Fan, Guo-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925632/
https://www.ncbi.nlm.nih.gov/pubmed/33679812
http://dx.doi.org/10.3389/fimmu.2021.647070