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Altered metabolic and inflammatory transcriptomics after cardiac surgery in neonates with congenital heart disease

The study examines the whole blood transcriptome profile before and after cardiopulmonary bypass (CPB) in neonates with hypoplastic left heart syndrome (HLHS), a severe form of congenital heart disease, that can develop low cardiac output syndrome (LCOS). Whole blood mRNA transcriptome profiles of 1...

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Detalles Bibliográficos
Autores principales: Jain, Parag N., Robertson, Matthew, Lasa, Javier J., Shekerdemian, Lara, Guffey, Danielle, Zhang, Yuhao, Lingappan, Krithika, Checchia, Paul, Coarfa, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925649/
https://www.ncbi.nlm.nih.gov/pubmed/33654130
http://dx.doi.org/10.1038/s41598-021-83882-x