A CCHFV DNA vaccine protects against heterologous challenge and establishes GP38 as immunorelevant in mice

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus that causes severe hemorrhagic fever disease in humans. Currently, no licensed CCHF vaccines exist, and the protective epitopes remain unclear. Previously, we tested a DNA vaccine expressing the M-segment glycoprotein precursor gene...

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Detalles Bibliográficos
Autores principales: Suschak, John J., Golden, Joseph W., Fitzpatrick, Collin J., Shoemaker, Charles J., Badger, Catherine V., Schmaljohn, Connie S., Garrison, Aura R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925670/
https://www.ncbi.nlm.nih.gov/pubmed/33654101
http://dx.doi.org/10.1038/s41541-021-00293-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925670/
https://www.ncbi.nlm.nih.gov/pubmed/33654101
http://dx.doi.org/10.1038/s41541-021-00293-9

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