Stabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replication

p18 is a key negative regulator of cell cycle progression and mediates cell cycle arrest at the G1/S phase. Ubiquitination is the prime mechanism in regulating p18 protein abundance. However, so far no post- translational regulator, especially DUBs, has been identified to regulate the protein stabil...

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Detalles Bibliográficos
Autores principales: Li, Yueshuo, Shi, Feng, Hu, Jianmin, Xie, Longlong, Zhao, Lin, Tang, Min, Luo, Xiangjian, Ye, Mao, Zheng, Hui, Zhou, Min, Liu, Na, Bode, Ann M., Fan, Jia, Zhou, Jian, Gao, Qiang, Qiu, Shuangjian, Wu, Weizhong, Zhang, Xin, Liao, Weihua, Cao, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925679/
https://www.ncbi.nlm.nih.gov/pubmed/33654169
http://dx.doi.org/10.1038/s41698-021-00153-8

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