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TNFRSF13B Diversification Fueled by B Cell Responses to Environmental Challenges—A Hypothesis
B cell differentiation and memory are controlled by the transmembrane activator and CAML interactor (TACI), a receptor encoded by TNFRSF13B. TNFRSF13B mutations are frequently found in common variable immunodeficiency (CVID) and in IgA -deficiency; yet, ~98% of those with mutant TNFRSF13B are health...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925820/ https://www.ncbi.nlm.nih.gov/pubmed/33679786 http://dx.doi.org/10.3389/fimmu.2021.634544 |