IL10- and IL35-Secreting MutuDC Lines Act in Cooperation to Inhibit Memory T Cell Activation Through LAG-3 Expression

Dendritic cells (DCs) are professional antigen-presenting cells involved in the initiation of immune responses. We generated a tolerogenic DC (tolDC) line that constitutively secretes interleukin-10 (IL10-DCs), expressed lower levels of co-stimulatory and MHCII molecules upon stimulation, and induce...

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Detalles Bibliográficos
Autores principales: Koga, Marianna M., Engel, Adrien, Pigni, Matteo, Lavanchy, Christine, Stevanin, Mathias, Laversenne, Vanessa, Schneider, Bernard L., Acha-Orbea, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925845/
https://www.ncbi.nlm.nih.gov/pubmed/33679743
http://dx.doi.org/10.3389/fimmu.2021.607315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925845/
https://www.ncbi.nlm.nih.gov/pubmed/33679743
http://dx.doi.org/10.3389/fimmu.2021.607315

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