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From the Genetics of Ankylosing Spondylitis to New Biology and Drug Target Discovery

Genome-wide association studies (GWAS) have identified 113 single nucleotide polymorphisms (SNPs) affecting the risk of developing ankylosing spondylitis (AS), and an on-going GWAS study will likely identify 100+ new risk loci. The translation of genetic findings to novel disease biology and treatme...

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Detalles Bibliográficos
Autores principales: Nancy, Zaarour, Yan, Li, Hui, Shi, Paul, Bowness, Liye, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925991/
https://www.ncbi.nlm.nih.gov/pubmed/33679768
http://dx.doi.org/10.3389/fimmu.2021.624632