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SIRT3 promotion reduces resistance to cisplatin in lung cancer by modulating the FOXO3/CDT1 axis

BACKGROUND: Cisplatin is an extensively used chemotherapy agent for lung cancer, but its drug resistance serves as a huge obstacle for chemotherapy failure of lung cancer patients. Hence, researchers aimed to determine role of sirtuin 3 (SIRT3) considering its action in cisplatin resistance of lung...

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Detalles Bibliográficos
Autores principales: Cao, Yang, Li, Ping, Wang, Haicun, Li, Lei, Li, Quanwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926010/
https://www.ncbi.nlm.nih.gov/pubmed/33655712
http://dx.doi.org/10.1002/cam4.3728