High Concentrations of Etanercept Reduce Human Islet Function and Integrity

BACKGROUND: Most islet transplant groups worldwide routinely use the TNFα inhibitor Etanercept in their peri-transplant protocols. Surprisingly, there have been no published dose-response studies on the effects of Etanercept on human islets. Our study aimed to address this by treating cultured human...

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Detalles Bibliográficos
Autores principales: Brandhorst, Daniel, Brandhorst, Heide, Acreman, Samuel, Abraham, Anju, Johnson, Paul R V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926188/
https://www.ncbi.nlm.nih.gov/pubmed/33679137
http://dx.doi.org/10.2147/JIR.S294663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926188/
https://www.ncbi.nlm.nih.gov/pubmed/33679137
http://dx.doi.org/10.2147/JIR.S294663

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