Cargando…
High Concentrations of Etanercept Reduce Human Islet Function and Integrity
BACKGROUND: Most islet transplant groups worldwide routinely use the TNFα inhibitor Etanercept in their peri-transplant protocols. Surprisingly, there have been no published dose-response studies on the effects of Etanercept on human islets. Our study aimed to address this by treating cultured human...
Autores principales: | Brandhorst, Daniel, Brandhorst, Heide, Acreman, Samuel, Abraham, Anju, Johnson, Paul R V |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926188/ https://www.ncbi.nlm.nih.gov/pubmed/33679137 http://dx.doi.org/10.2147/JIR.S294663 |
Ejemplares similares
-
The ischaemic preconditioning paradox and its implications for islet isolation from heart-beating and non heart-beating donors
por: Brandhorst, Daniel, et al.
Publicado: (2022) -
Proteomic Profiling Reveals the Ambivalent Character of the Mesenchymal Stem Cell Secretome: Assessing the Effect of Preconditioned Media on Isolated Human Islets
por: Brandhorst, Heide, et al.
Publicado: (2020) -
Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity
por: Brandhorst, Heide, et al.
Publicado: (2018) -
Comparison of Neutral Proteases and Collagenase Class I as Essential Enzymes for Human Islet Isolation
por: Brandhorst, Heide, et al.
Publicado: (2015) -
Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation
por: Brandhorst, Heide, et al.
Publicado: (2018)