MITOL promotes cell survival by degrading Parkin during mitophagy

Parkin promotes cell survival by removing damaged mitochondria via mitophagy. However, although some studies have suggested that Parkin induces cell death, the regulatory mechanism underlying the dual role of Parkin remains unknown. Herein, we report that mitochondrial ubiquitin ligase (MITOL/MARCH5...

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Detalles Bibliográficos
Autores principales: Shiiba, Isshin, Takeda, Keisuke, Nagashima, Shun, Ito, Naoki, Tokuyama, Takeshi, Yamashita, Shun‐Ichi, Kanki, Tomotake, Komatsu, Toru, Urano, Yasuteru, Fujikawa, Yuuta, Inatome, Ryoko, Yanagi, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926225/
https://www.ncbi.nlm.nih.gov/pubmed/33565245
http://dx.doi.org/10.15252/embr.201949097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926225/
https://www.ncbi.nlm.nih.gov/pubmed/33565245
http://dx.doi.org/10.15252/embr.201949097

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