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Transient deSUMOylation of IRF2BP proteins controls early transcription in EGFR signaling

Molecular switches are essential modules in signaling networks and transcriptional reprogramming. Here, we describe a role for small ubiquitin‐related modifier SUMO as a molecular switch in epidermal growth factor receptor (EGFR) signaling. Using quantitative mass spectrometry, we compare the endoge...

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Detalles Bibliográficos
Autores principales: Barysch, Sina V, Stankovic‐Valentin, Nicolas, Miedema, Tim, Karaca, Samir, Doppel, Judith, Nait Achour, Thiziri, Vasudeva, Aarushi, Wolf, Lucie, Sticht, Carsten, Urlaub, Henning, Melchior, Frauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926235/
https://www.ncbi.nlm.nih.gov/pubmed/33480129
http://dx.doi.org/10.15252/embr.201949651