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Succinylation of H3K122 destabilizes nucleosomes and enhances transcription

Histone post‐translational modifications (PTMs) are key players in chromatin regulation. The identification of novel histone acylations raises important questions regarding their role in transcription. In this study, we characterize the role of an acylation on the lateral surface of the histone octa...

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Detalles Bibliográficos
Autores principales: Zorro Shahidian, Lara, Haas, Mariska, Le Gras, Stephanie, Nitsch, Sandra, Mourão, André, Geerlof, Arie, Margueron, Raphael, Michaelis, Jens, Daujat, Sylvain, Schneider, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926236/
https://www.ncbi.nlm.nih.gov/pubmed/33512761
http://dx.doi.org/10.15252/embr.202051009