CUL2(LRR1), TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle

The eukaryotic replisome is disassembled in each cell cycle, dependent upon ubiquitylation of the CMG helicase. Studies of Saccharomyces cerevisiae, Caenorhabditis elegans and Xenopus laevis have revealed surprising evolutionary diversity in the ubiquitin ligases that control CMG ubiquitylation, but...

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Detalles Bibliográficos
Autores principales: Villa, Fabrizio, Fujisawa, Ryo, Ainsworth, Johanna, Nishimura, Kohei, Lie‐A‐Ling, Michael, Lacaud, Georges, Labib, Karim PM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926238/
https://www.ncbi.nlm.nih.gov/pubmed/33590678
http://dx.doi.org/10.15252/embr.202052164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926238/
https://www.ncbi.nlm.nih.gov/pubmed/33590678
http://dx.doi.org/10.15252/embr.202052164

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