Phosphodiesterase 4A confers resistance to PGE2‐mediated suppression in CD25(+)/CD54(+) NK cells

Inadequate persistence of tumor‐infiltrating natural killer (NK) cells is associated with poor prognosis in cancer patients. The solid tumor microenvironment is characterized by the presence of immunosuppressive factors, including prostaglandin E2 (PGE2), that limit NK cell persistence. Here, we inv...

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Detalles Bibliográficos
Autores principales: Chen, Ziqing, Yang, Ying, Neo, Shi Y, Shi, Hao, Chen, Yi, Wagner, Arnika K, Larsson, Karin, Tong, Le, Jakobsson, Per‐Johan, Alici, Evren, Wu, Jing, Cao, Yihai, Wang, Kai, Liu, Lisa L, Mao, Yumeng, Sarhan, Dhifaf, Lundqvist, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926252/
https://www.ncbi.nlm.nih.gov/pubmed/33480074
http://dx.doi.org/10.15252/embr.202051329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926252/
https://www.ncbi.nlm.nih.gov/pubmed/33480074
http://dx.doi.org/10.15252/embr.202051329

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