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Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2-b][1,2,4]triazole-6(5H)-ones as Possible Anticancer Agents

The present paper is devoted to the search for drug-like molecules with anticancer properties using the thiazolo[3,2-b][1,2,4]triazole-6-one scaffold. A series of 24 novel thiazolo-[3,2-b][1,2,4]triazole-6-ones with 5-aryl(heteryl)idene- and 5-aminomethylidene-moieties has been synthesized employing...

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Detalles Bibliográficos
Autores principales: Holota, Serhii, Komykhov, Sergiy, Sysak, Stepan, Gzella, Andrzej, Cherkas, Andriy, Lesyk, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926352/
https://www.ncbi.nlm.nih.gov/pubmed/33671733
http://dx.doi.org/10.3390/molecules26041162