Cargando…

Integrin-Linked Kinase Links Integrin Activation to Invadopodia Function and Invasion via the p(T567)-Ezrin/NHERF1/NHE1 Pathway

Tumor cell invasion depends largely on degradation of the extracellular matrix (ECM) by protease-rich structures called invadopodia, whose formation and activity requires the convergence of signaling pathways engaged in cell adhesion, actin assembly, membrane regulation and ECM proteolysis. It is kn...

Descripción completa

Detalles Bibliográficos
Autores principales: Greco, Maria Raffaella, Moro, Loredana, Forciniti, Stefania, Alfarouk, Khalid, Cannone, Stefania, Cardone, Rosa Angela, Reshkin, Stephan Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926356/
https://www.ncbi.nlm.nih.gov/pubmed/33671549
http://dx.doi.org/10.3390/ijms22042162