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Ameliorating Fibrotic Phenotypes of Keloid Dermal Fibroblasts through an Epidermal Growth Factor-Mediated Extracellular Matrix Remodeling

Keloid and hypertrophic scars are skin fibrosis-associated disorders that exhibit an uncontrollable proliferation of fibroblasts and their subsequent contribution to the excessive accumulation of extracellular matrix (ECM) in the dermis. In this study, to elucidate the underlying mechanisms, we inve...

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Detalles Bibliográficos
Autores principales: Kim, Hyunbum, Anggradita, Laurensia Danis, Lee, Sun-Jae, Hur, Sung Sik, Bae, Joonsuk, Hwang, Nathaniel Suk-Yeon, Nam, Seung Min, Hwang, Yongsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926382/
https://www.ncbi.nlm.nih.gov/pubmed/33672186
http://dx.doi.org/10.3390/ijms22042198