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Proteolytic Cleavages in the VEGF Family: Generating Diversity among Angiogenic VEGFs, Essential for the Activation of Lymphangiogenic VEGFs

SIMPLE SUMMARY: Vascular endothelial growth factors (VEGFs) regulate the growth of blood and lymphatic vessels. Some of them induce the growth of blood vessels, and others the growth of lymphatic vessels. Blocking VEGF-A is used today to treat several types of cancer (“antiangiogenic therapy”). Howe...

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Detalles Bibliográficos
Autores principales: Künnapuu, Jaana, Bokharaie, Honey, Jeltsch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926383/
https://www.ncbi.nlm.nih.gov/pubmed/33672235
http://dx.doi.org/10.3390/biology10020167