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Biochemical Regulation of the Glyoxalase System in Response to Insulin Signaling

Methylglyoxal (MG) is a reactive glycation metabolite and potentially induces dicarbonyl stress. The production of MG in cells is increased along with an increase in carbohydrate metabolism. The efficiency of the glyoxalase system, consisting of glyoxalase 1 (GlxI) and glyoxalase 2 (GlxII), is cruci...

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Detalles Bibliográficos
Autores principales: Lee, Der-Yen, Lin, Yu-Chin, Chang, Geen-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926409/
https://www.ncbi.nlm.nih.gov/pubmed/33671767
http://dx.doi.org/10.3390/antiox10020326