A Sprouty4 Mutation Identified in Kallmann Syndrome Increases the Inhibitory Potency of the Protein towards FGF and Connected Processes

Kallmann syndrome is the result of innate genetic defects in the fibroblast growth factor (FGF) regulated signaling network causing diminished signal transduction. One of the rare mutations associated with the syndrome alters the Sprouty (Spry)4 protein by converting the serine at position 241 into...

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Detalles Bibliográficos
Autores principales: Stütz, Astrid, Kamptner, Anna Z. M., Sutterlüty, Hedwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926442/
https://www.ncbi.nlm.nih.gov/pubmed/33670044
http://dx.doi.org/10.3390/ijms22042145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926442/
https://www.ncbi.nlm.nih.gov/pubmed/33670044
http://dx.doi.org/10.3390/ijms22042145

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