Augmented Therapeutic Potential of Glutaminase Inhibitor CB839 in Glioblastoma Stem Cells Using Gold Nanoparticle Delivery

Gold nanoparticles (Au NPs) are studied as delivery systems to enhance the effect of the glutaminase1 inhibitor CB839, a promising drug candidate already in clinical trials for tumor treatments. Au NPs were synthesized using a bottom-up approach and covered with polymers able to bind CB839 as a Au-p...

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Detalles Bibliográficos
Autores principales: Giesen, Beatriz, Nickel, Ann-Christin, Barthel, Juri, Kahlert, Ulf Dietrich, Janiak, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926460/
https://www.ncbi.nlm.nih.gov/pubmed/33672398
http://dx.doi.org/10.3390/pharmaceutics13020295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926460/
https://www.ncbi.nlm.nih.gov/pubmed/33672398
http://dx.doi.org/10.3390/pharmaceutics13020295

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