The Influence of Equipment Design and Process Parameters on Granule Breakage in a Semi-Continuous Fluid Bed Dryer after Continuous Twin-Screw Wet Granulation

The drying unit of a continuous from-powder-to-tablet manufacturing line based on twin-screw granulation (TSG) is a crucial intermediate process step to achieve the desired tablet quality. Understanding the size reduction of pharmaceutical granules before, during, and after the fluid bed drying proc...

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Detalles Bibliográficos
Autores principales: Ryckaert, Alexander, Ghijs, Michael, Portier, Christoph, Djuric, Dejan, Funke, Adrian, Vervaet, Chris, De Beer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926462/
https://www.ncbi.nlm.nih.gov/pubmed/33672389
http://dx.doi.org/10.3390/pharmaceutics13020293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926462/
https://www.ncbi.nlm.nih.gov/pubmed/33672389
http://dx.doi.org/10.3390/pharmaceutics13020293

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