Preclinical Pharmacokinetics and Biodistribution of Anticancer Dinuclear Palladium(II)-Spermine Complex (Pd(2)Spm) in Mice

Palladium-based compounds are regarded as potential analogs to platinum anticancer drugs with improved properties. The present study assessed the pharmacokinetics and biodistribution of a dinuclear palladium(II)-spermine chelate (Pd(2)Spm), which has previously been shown to possess promising in vit...

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Detalles Bibliográficos
Autores principales: Vojtek, Martin, Gonçalves-Monteiro, Salomé, Pinto, Edgar, Kalivodová, Sára, Almeida, Agostinho, Marques, Maria P. M., Batista de Carvalho, Ana L. M., Martins, Clara B., Mota-Filipe, Helder, Ferreira, Isabel M. P. L. V. O., Diniz, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926495/
https://www.ncbi.nlm.nih.gov/pubmed/33672377
http://dx.doi.org/10.3390/ph14020173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926495/
https://www.ncbi.nlm.nih.gov/pubmed/33672377
http://dx.doi.org/10.3390/ph14020173

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