Cargando…

Preclinical Pharmacokinetics and Biodistribution of Anticancer Dinuclear Palladium(II)-Spermine Complex (Pd(2)Spm) in Mice

Palladium-based compounds are regarded as potential analogs to platinum anticancer drugs with improved properties. The present study assessed the pharmacokinetics and biodistribution of a dinuclear palladium(II)-spermine chelate (Pd(2)Spm), which has previously been shown to possess promising in vit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vojtek, Martin, Gonçalves-Monteiro, Salomé, Pinto, Edgar, Kalivodová, Sára, Almeida, Agostinho, Marques, Maria P. M., Batista de Carvalho, Ana L. M., Martins, Clara B., Mota-Filipe, Helder, Ferreira, Isabel M. P. L. V. O., Diniz, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926495/ https://www.ncbi.nlm.nih.gov/pubmed/33672377 http://dx.doi.org/10.3390/ph14020173

Ejemplares similares

Impact of the Pd(2)Spm (Spermine) Complex on the Metabolism of Triple-Negative Breast Cancer Tumors of a Xenograft Mouse Model
por: Carneiro, Tatiana J., et al.
Publicado: (2021)

Pd(2)Spermine Complex Shows Cancer Selectivity and Efficacy to Inhibit Growth of Triple-Negative Breast Tumors in Mice
por: Vojtek, Martin, et al.
Publicado: (2022)

Metabolic Impact of Anticancer Drugs Pd(2)Spermine and Cisplatin on the Brain of Healthy Mice
por: Carneiro, Tatiana J., et al.
Publicado: (2022)

Effect of Pd(2)Spermine on Mice Brain-Liver Axis Metabolism Assessed by NMR Metabolomics
por: Carneiro, Tatiana J., et al.
Publicado: (2022)

Dinuclear Nickel(I) and Palladium(I) Complexes for Highly Active Transformations of Organic Compounds
por: Inatomi, Takahiro, et al.
Publicado: (2018)

SPM Bulletin 13
por: Tsaban, B
Publicado: (2005)

SPM: A history
por: Ashburner, John
Publicado: (2012)

SPM 2020 Editorial
por: Li, Xin, et al.
Publicado: (2020)

Cyclometallated Palladium(II) Complexes: An Approach to the First Dinuclear Bis(iminophosphorane)phosphane-[C,N,S] Metallacycle
por: Rúa-Sueiro, Marcos, et al.
Publicado: (2022)

POAS4SPM: A Toolbox for SPM to Denoise Diffusion MRI Data
por: Tabelow, Karsten, et al.
Publicado: (2014)

Anti-Invasive and Anti-Proliferative Synergism between Docetaxel and a Polynuclear Pd-Spermine Agent
por: Batista de Carvalho, Ana L. M., et al.
Publicado: (2016)

Novel Insights into Mice Multi-Organ Metabolism upon Exposure to a Potential Anticancer Pd(II)-Agent
por: Carneiro, Tatiana J., et al.
Publicado: (2021)

Multinomial inference on distributed responses in SPM
por: Chumbley, J.R., et al.
Publicado: (2010)

Synthesis, characterization, molecular docking, and antimicrobial activities of dinuclear nickel(ii), palladium(ii), and platinum(iv) complexes
por: Ebrahim, Reem M. A., et al.
Publicado: (2023)

Synthesis and structures of dinuclear palladium complexes with 1,3-benzimidazolidine-2-thione and 1,3-imidazoline-2-thione
por: Lobana, Tarlok S., et al.
Publicado: (2023)

Antiviral effects of Lactobacillus ruminis SPM0211 and Bifidobacterium longum SPM1205 and SPM1206 on rotavirus-infected Caco-2 cells and a neonatal mouse model
por: Kang, Joo Yeon, et al.
Publicado: (2015)

SPERMINE OXIDASE: AN AMINE OXIDASE WITH SPECIFICITY FOR SPERMINE AND SPERMIDINE
por: Hirsch, James G.
Publicado: (1953)

The polymine spermine regulates osteogenic differentiation in adipose stem cells
por: Tjabringa, GS, et al.
Publicado: (2008)

Regulatory guidelines and preclinical tools to study the biodistribution of RNA therapeutics
por: Vervaeke, P., et al.
Publicado: (2022)

Evaluation of the Cytotoxic Effect of Pd(2)Spm against Prostate Cancer through Vibrational Microspectroscopies
por: Laginha, Raquel C., et al.
Publicado: (2023)

Spermine oxidase (SMO) activity in breast tumor tissues and biochemical analysis of the anticancer spermine analogues BENSpm and CPENSpm
por: Cervelli, Manuela, et al.
Publicado: (2010)

Veeco SPM Conference & Users Meeting
por: Collective
Publicado: (2004)

Epileptogenic Zone Localization in Refractory Epilepsy by FDG-PET: The Comparison of SPM and SPM-CAT With Different Parameter Settings
por: Bacon, Eric Jacob, et al.
Publicado: (2021)

Potential energy of dinuclear system
por: Adamian, G G, et al.
Publicado: (1993)

Scan speed control for tapping mode SPM
por: Meshtcheryakov, Aleksey V, et al.
Publicado: (2012)

EEG and MEG Data Analysis in SPM8
por: Litvak, Vladimir, et al.
Publicado: (2011)

GeoSPM: Geostatistical parametric mapping for medicine
por: Engleitner, Holger, et al.
Publicado: (2022)

Biodistribution of Mesenchymal Stem/Stromal Cells in a Preclinical Setting
por: Sensebé, Luc, et al.
Publicado: (2013)

Comparative strategies for stem cell biodistribution in a preclinical study
por: Wang, Fang, et al.
Publicado: (2019)

Multi-Organ NMR Metabolomics to Assess In Vivo Overall Metabolic Impact of Cisplatin in Mice
por: Carneiro, Tatiana J., et al.
Publicado: (2019)

VBM with viscous fluid registration of gray matter segments in SPM
por: Pereira, Joao M. S., et al.
Publicado: (2013)

Myosin Va interacts with the exosomal protein spermine synthase
por: Dolce, Luciano G., et al.
Publicado: (2019)

Optimal geometry for a quartz multipurpose SPM sensor
por: Stirling, Julian
Publicado: (2013)

Mass parameters for dinuclear system
por: Adamian, G G, et al.
Publicado: (1993)

THE EFFECT OF SPERMINE ON TUBERCLE BACILLI
por: Hirsch, James G., et al.
Publicado: (1952)

Influence of Group on Individual Subject Maps in SPM Voxel Based Morphometry
por: Michael, Andrew M., et al.
Publicado: (2016)

Insights into Nuclear G-Protein-Coupled Receptors as Therapeutic Targets in Non-Communicable Diseases
por: Gonçalves-Monteiro, Salomé, et al.
Publicado: (2021)

Localization of spermine binding sites in 23S rRNA by photoaffinity labeling: parsing the spermine contribution to ribosomal 50S subunit functions
por: Xaplanteri, Maria A., et al.
Publicado: (2005)

Electronic Structure of Dinuclear Gold(I) Complexes
por: Foley, Janet B., et al.
Publicado: (1999)

Non-equidistant scanning approach for millimetre-sized SPM measurements
por: Klapetek, Petr, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_p2jp73chnsvkfjf7r7fgvl8flj