Decoding the Molecular Effects of Atovaquone Linked Resistant Mutations on Plasmodium falciparum Cytb-ISP Complex in the Phospholipid Bilayer Membrane

Atovaquone (ATQ) is a drug used to prevent and treat malaria that functions by targeting the Plasmodium falciparum cytochrome b (PfCytb) protein. PfCytb catalyzes the transmembrane electron transfer (ET) pathway which maintains the mitochondrial membrane potential. The ubiquinol substrate binding si...

Descripción completa

Detalles Bibliográficos
Autores principales: Chebon-Bore, Lorna, Sanyanga, Taremekedzwa Allan, Manyumwa, Colleen Varaidzo, Khairallah, Afrah, Tastan Bishop, Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926518/
https://www.ncbi.nlm.nih.gov/pubmed/33670016
http://dx.doi.org/10.3390/ijms22042138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926518/
https://www.ncbi.nlm.nih.gov/pubmed/33670016
http://dx.doi.org/10.3390/ijms22042138

Ejemplares similares