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Decoding the Molecular Effects of Atovaquone Linked Resistant Mutations on Plasmodium falciparum Cytb-ISP Complex in the Phospholipid Bilayer Membrane

Atovaquone (ATQ) is a drug used to prevent and treat malaria that functions by targeting the Plasmodium falciparum cytochrome b (PfCytb) protein. PfCytb catalyzes the transmembrane electron transfer (ET) pathway which maintains the mitochondrial membrane potential. The ubiquinol substrate binding si...

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Detalles Bibliográficos
Autores principales:	Chebon-Bore, Lorna, Sanyanga, Taremekedzwa Allan, Manyumwa, Colleen Varaidzo, Khairallah, Afrah, Tastan Bishop, Özlem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926518/ https://www.ncbi.nlm.nih.gov/pubmed/33670016 http://dx.doi.org/10.3390/ijms22042138

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