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Respiratory Syncytial Virus (RSV) G Protein Vaccines With Central Conserved Domain Mutations Induce CX3C-CX3CR1 Blocking Antibodies

Respiratory syncytial virus (RSV) infection can cause bronchiolitis, pneumonia, morbidity, and some mortality, primarily in infants and the elderly, for which no vaccine is available. The RSV attachment (G) protein contains a central conserved domain (CCD) with a CX3C motif implicated in the inducti...

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Detalles Bibliográficos
Autores principales: Bergeron, Harrison C., Murray, Jackelyn, Nuñez Castrejon, Ana M., DuBois, Rebecca M., Tripp, Ralph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926521/
https://www.ncbi.nlm.nih.gov/pubmed/33672319
http://dx.doi.org/10.3390/v13020352