Cargando…

Respiratory Syncytial Virus (RSV) G Protein Vaccines With Central Conserved Domain Mutations Induce CX3C-CX3CR1 Blocking Antibodies

Respiratory syncytial virus (RSV) infection can cause bronchiolitis, pneumonia, morbidity, and some mortality, primarily in infants and the elderly, for which no vaccine is available. The RSV attachment (G) protein contains a central conserved domain (CCD) with a CX3C motif implicated in the inducti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bergeron, Harrison C., Murray, Jackelyn, Nuñez Castrejon, Ana M., DuBois, Rebecca M., Tripp, Ralph A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926521/ https://www.ncbi.nlm.nih.gov/pubmed/33672319 http://dx.doi.org/10.3390/v13020352

Ejemplares similares

Immune Prophylaxis Targeting the Respiratory Syncytial Virus (RSV) G Protein
por: Bergeron, Harrison C., et al.
Publicado: (2023)

Immunogenicity and protective efficacy of an RSV G S177Q central conserved domain nanoparticle vaccine
por: Bergeron, Harrison C., et al.
Publicado: (2023)

Anti-G protein antibodies targeting the RSV G protein CX3C chemokine region improve the interferon response
por: Bergeron, Harrison C., et al.
Publicado: (2023)

Probenecid Inhibits Respiratory Syncytial Virus (RSV) Replication
por: Murray, Jackelyn, et al.
Publicado: (2022)

Modulating neurotoxicity through CX3CL1/CX3CR1 signaling
por: Limatola, Cristina, et al.
Publicado: (2014)

The Impact of the CX3CL1/CX3CR1 Axis in Neurological Disorders
por: Pawelec, Paulina, et al.
Publicado: (2020)

CX3CR1 in multiple sclerosis
por: Rivest, Serge
Publicado: (2015)

CX3CL1–CX3CR1 Axis: A New Player in Coeliac Disease Pathogenesis
por: Fernández-Prieto, Marta, et al.
Publicado: (2019)

CX3CL1/CX3CR1 in Alzheimer's Disease: A Target for Neuroprotection
por: Chen, Peiqing, et al.
Publicado: (2016)

Role of CX3CL1/CX3CR1 Signaling Axis Activity in Osteoporosis
por: Wojdasiewicz, Piotr, et al.
Publicado: (2019)

Involvement of CX3CL1/CX3CR1 Signaling in Spinal Long Term Potentiation
por: Bian, Chao, et al.
Publicado: (2015)

Regulation and function of CX3CR1 and its ligand CX3CL1 in kidney disease
por: von Vietinghoff, Sibylle, et al.
Publicado: (2021)

Nanoparticle Vaccines Encompassing the Respiratory Syncytial Virus (RSV) G Protein CX3C Chemokine Motif Induce Robust Immunity Protecting from Challenge and Disease
por: Jorquera, Patricia A., et al.
Publicado: (2013)

CX3CR1 and malignant progression of glioma
por: Lee, Sungho, et al.
Publicado: (2021)

Layer-By-Layer Nanoparticle Vaccines Carrying the G Protein CX3C Motif Protect against RSV Infection and Disease
por: Jorquera, Patricia A., et al.
Publicado: (2015)

Hydrogen Sulfide Inhibits the Development of Atherosclerosis with Suppressing CX3CR1 and CX3CL1 Expression
por: Zhang, Huili, et al.
Publicado: (2012)

CX3CL1/CX3CR1 Axis, as the Therapeutic Potential in Renal Diseases: Friend or Foe?
por: Zhuang, Quan, et al.
Publicado: (2017)

Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation
por: Rowinska, Zuzanna, et al.
Publicado: (2017)

Pharmacological depletion of microglia alleviates neuronal and vascular damage in the diabetic CX3CR1-WT retina but not in CX3CR1-KO or hCX3CR1(I249/M280)-expressing retina
por: Church, Kaira A., et al.
Publicado: (2023)

CX(3)CR1(+) CD115(+) CD135(+) common macrophage/DC precursors and the role of CX(3)CR1 in their response to inflammation
por: Auffray, Cedric, et al.
Publicado: (2009)

The Chemokine CX3CL1 (Fractalkine) and its Receptor CX3CR1: Occurrence and Potential Role in Osteoarthritis
por: Wojdasiewicz, Piotr, et al.
Publicado: (2014)

Involvement of CX3CL1/CX3CR1 axis in etanercept therapy for patients with active rheumatoid arthritis
por: Sato, Michihito, et al.
Publicado: (2011)

Therapeutic intervention of inflammatory/immune diseases by inhibition of the fractalkine (CX3CL1)-CX3CR1 pathway
por: Imai, Toshio, et al.
Publicado: (2016)

Microglia and Aging: The Role of the TREM2–DAP12 and CX3CL1-CX3CR1 Axes
por: Mecca, Carmen, et al.
Publicado: (2018)

Prevention of lipopolysaccharide-induced preterm labor by the lack of CX3CL1-CX3CR1 interaction in mice
por: Mizoguchi, Mika, et al.
Publicado: (2018)

Fractalkine Signalling (CX(3)CL1/CX(3)CR1 Axis) as an Emerging Target in Coronary Artery Disease
por: Loh, Shu Xian, et al.
Publicado: (2023)

Microglia, seen from the CX(3)CR1 angle
por: Wolf, Yochai, et al.
Publicado: (2013)

Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration
por: Luhmann, Ulrich F.O., et al.
Publicado: (2013)

The deficiency of CX3CL1/CX3CR1 system ameliorates high fructose diet-induced kidney injury by regulating NF-κB pathways in CX3CR1-knock out mice
por: Yu, Yong-Wu, et al.
Publicado: (2018)

CX(3)CR1 Is Expressed by Human B Lymphocytes and Meditates CX(3)CL1 Driven Chemotaxis of Tonsil Centrocytes
por: Corcione, Anna, et al.
Publicado: (2009)

Fractalkine (CX3CL1) and Its Receptor CX3CR1 May Contribute to Increased Angiogenesis in Diabetic Placenta
por: Szukiewicz, Dariusz, et al.
Publicado: (2013)

Repopulating retinal microglia restore endogenous organization and function under CX3CL1-CX3CR1 regulation
por: Zhang, Yikui, et al.
Publicado: (2018)

CX3CL1 and CX3CR1 could be a relevant molecular axis in the pathophysiology of idiopathic pulmonary fibrosis
por: Rivas-Fuentes, Selma, et al.
Publicado: (2020)

Tenophages: a novel macrophage-like tendon cell population expressing CX3CL1 and CX3CR1
por: Lehner, Christine, et al.
Publicado: (2019)

Cochlear resident macrophage mediates development of ribbon synapses via CX3CR1/CX3CL1 axis
por: Song, Xinyu, et al.
Publicado: (2022)

Microparticle RSV Vaccines Presenting the G Protein CX3C Chemokine Motif in the Context of TLR Signaling Induce Protective Th1 Immune Responses and Prevent Pulmonary Eosinophilia Post-Challenge
por: Powell, Thomas J., et al.
Publicado: (2022)

Respiratory Syncytial Virus Uses CX3CR1 as a Receptor on Primary Human Airway Epithelial Cultures
por: Johnson, Sara M., et al.
Publicado: (2015)

The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy
por: Chaudhri, Apoorvi, et al.
Publicado: (2023)

RSV Replication, Transmission, and Disease Are Influenced by the RSV G Protein
por: Bergeron, Harrison C., et al.
Publicado: (2022)

Sirtuin 3 promotes microglia migration by upregulating CX3CR1
por: Cao, Runjing, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_u4qqu4u4tve5a9qqvpd391sbed